购物车
- 全部删除
- 您的购物车当前为空
Anti-Neuroserpin Antibody (9J619) 是一种 Rabbit 抗体,靶向 Neuroserpin。Anti-Neuroserpin Antibody (9J619) 可用于 ELISA。
Anti-Neuroserpin Antibody (9J619) 是一种 Rabbit 抗体,靶向 Neuroserpin。Anti-Neuroserpin Antibody (9J619) 可用于 ELISA。
产品描述 | Anti-Neuroserpin Antibody (9J619) is a Rabbit antibody targeting Neuroserpin. Anti-Neuroserpin Antibody (9J619) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9J619 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinI1 (rh SerpinI1; TMPY-01241; NP_005016.1; Met 1-Leu 410). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Neuroserpin, also known as Protease inhibitor 12 and SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons. Neuroserpin is predominantly expressed in the brain, and is expressed in the late stages of neurogenesis during the process of synapse formation. Overexpression of neuroserpin in an anterior pituitary corticotroph cell line results in the extension of neurite-like processes, suggesting that neuroserpin may play a role in cell communication, cell adhesion, and/or cell migration. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. Neuroserpin may also protect neurons from cell damage by tissue-type plasminogen activator. Defects of neuroserpin are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B). |
偶联 | Unconjugated |
免疫原 | Recombinant Human SerpinI1 protein (TMPY-01241) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
评论内容