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Anti-Neuroserpin Antibody (9J619)

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产品编号 TMAY-01649

Anti-Neuroserpin Antibody (9J619) 是一种 Rabbit 抗体,靶向 Neuroserpin。Anti-Neuroserpin Antibody (9J619) 可用于 ELISA。

Anti-Neuroserpin Antibody (9J619)

Anti-Neuroserpin Antibody (9J619)

Rating icon 还可以
产品编号 TMAY-01649

Anti-Neuroserpin Antibody (9J619) 是一种 Rabbit 抗体,靶向 Neuroserpin。Anti-Neuroserpin Antibody (9J619) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-Neuroserpin Antibody (9J619) is a Rabbit antibody targeting Neuroserpin. Anti-Neuroserpin Antibody (9J619) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
9J619
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human SerpinI1 (rh SerpinI1; TMPY-01241; NP_005016.1; Met 1-Leu 410).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Neuroserpin, also known as Protease inhibitor 12 and SERPINI1, is a secreted protein that belongs to the serpin family. Neuroserpin is a serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. Serine protease inhibitors of the serpin superfamily are involved in many cellular processes. Neuroserpin was first identified as a protein secreted from the axons of dorsal root ganglion neurons. Neuroserpin is predominantly expressed in the brain, and is expressed in the late stages of neurogenesis during the process of synapse formation. Overexpression of neuroserpin in an anterior pituitary corticotroph cell line results in the extension of neurite-like processes, suggesting that neuroserpin may play a role in cell communication, cell adhesion, and/or cell migration. Neuroserpin may be involved in the formation or reorganization of synaptic connections, as well as synaptic plasticity in the adult nervous system. Neuroserpin may also protect neurons from cell damage by tissue-type plasminogen activator. Defects of neuroserpin are the cause of familial encephalopathy with neuroserpin inclusion bodies (FEN1B).
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human SerpinI1 protein (TMPY-01241)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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