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顶部生物活性储存和溶解信息计算器

Anti-SATB1 Antibody (9Q281)

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Anti-SATB1 Antibody (9Q281)
产品编号 TMAC-03687
别名 Special AT-rich sequence-binding protein 1, Special AT rich sequence binding protein 1 (binds to nuclear matrix/scaffold associating DNA), Special AT rich sequence binding protein 1, SATB1_HUMAN, SATB homeobox 1, SATB 1, DNA-binding protein SATB1, DNA binding protein SATB1

Anti-SATB1 Antibody (9Q281) 是一种 Rabbit 抗体，靶向 SATB1。Anti-SATB1 Antibody (9Q281) 可用于 WB,ICC/IF,IHC,IP,FCM。

Anti-SATB1 Antibody (9Q281)

Anti-SATB1 Antibody (9Q281)

Rating icon 还可以
Anti-SATB1 Antibody (9Q281)
产品编号 TMAC-03687 别名 Special AT-rich sequence-binding protein 1, Special AT rich sequence binding protein 1 (binds to nuclear matrix/scaffold associating DNA), Special AT rich sequence binding protein 1, SATB1_HUMAN, SATB homeobox 1, SATB 1, DNA-binding protein SATB1, DNA binding protein SATB1

Anti-SATB1 Antibody (9Q281) 是一种 Rabbit 抗体，靶向 SATB1。Anti-SATB1 Antibody (9Q281) 可用于 WB,ICC/IF,IHC,IP,FCM。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-SATB1 Antibody (9Q281) is a Rabbit antibody targeting SATB1. Anti-SATB1 Antibody (9Q281) can be used in WB,ICC/IF,IHC,IP,FCM.
别名Special AT-rich sequence-binding protein 1, Special AT rich sequence binding protein 1 (binds to nuclear matrix/scaffold associating DNA), Special AT rich sequence binding protein 1, SATB1_HUMAN, SATB homeobox 1, SATB 1, DNA-binding protein SATB1, DNA binding protein SATB1
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of SATB1 on human thymus lysates using anti-SATB1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat spleen tissue using anti-SATB1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse thymus tissue using anti-SATB1 antibody. Counter stained with hematoxylin.
4. Flow cytometric analysis of Jurkat cells with SATB1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
WB
ICC/IF
IHC
IP
FCM
推荐剂量
WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The homeoproteins CCAAT displacement protein (CDP) and special AT-rich sequence binding protein 1 (SATB1) are transcriptional repressors of many cellular genes, and they participate in cell development and cell type differentiation. SATB1 is expressed primarily in thymocytes, and, like CDP, it also contains a distinct homeobox DNA-binding domain that is essential for DNA binding. SATB1 and CDP interact through these homeodomains and synergistically function as mediators of gene expression. SATB1 contains an additional domain that has a higher affinity for DNA and specifically facilitates the direct association between SATB1 and the nuclear matrix attachment regions (MARs) of DNA. MARs are specific DNA sequences that bind to the nuclear matrix and form the base of chromosomal loops that organize the chromosomes and regulate DNA transcription and replication within the nucleus. The association of SATB1 with the core unwinding element within the base-unpairing region of MARs requires both the MAR and homeobox binding domains of SATB1.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q01826
化学信息
分子量Theoretical: 100 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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