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GDF11 Protein, Human, Recombinant (His & SUMO)

Synonyms: Growth/differentiation factor 11, GDF-11, GDF11, Bone morphogenetic protein 11 (BMP-11), BMP11
货号 TMPH-01413 一键复制产品信息
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Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. GDF11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 28.5 kDa and the accession number is O95390.

GDF11 Protein, Human, Recombinant (His & SUMO)

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货号 TMPH-01413

别名 Growth/differentiation factor 11, GDF-11, GDF11, Bone morphogenetic protein 11 (BMP-11), BMP11

Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. GDF11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 28.5 kDa and the accession number is O95390.

GDF11 Protein, Human, Recombinant (His & SUMO)
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规格价格库存数量
5 μg
¥ 489
20日内发货
10 μg
¥ 797
20日内发货
20 μg
¥ 1,320
20日内发货
50 μg
¥ 1,970
20日内发货
100 μg
¥ 2,680
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200 μg
¥ 4,160
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500 μg
¥ 7,490
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1 mg
¥ 11,700
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产品介绍

生物活性
产品描述
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. GDF11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 28.5 kDa and the accession number is O95390.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3.
种属
Human
表达系统
E. coli
标签N-6xHis-SUMO
蛋白编号O95390
氨基酸序列NLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
蛋白构建299-407 aa
蛋白纯度
> 90% as determined by SDS-PAGE.
缓冲液Tris-based buffer, 50% glycerol
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名Growth/differentiation factor 11, GDF-11, GDF11, Bone morphogenetic protein 11 (BMP-11), BMP11
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量28.5 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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关键词

GDF 11BMP-11BMP 11
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