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顶部生物活性储存和溶解信息计算器

Anti-Phospho-FADD (Ser191) Polyclonal Antibody

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Anti-Phospho-FADD (Ser191) Polyclonal Antibody
产品编号 TMAC-01423
别名 p-FADD (Ser191), p-FADD (S191), FADD (p-Ser191), FADD (p-S191)

Anti-Phospho-FADD (Ser191) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FADD (Ser191)。Anti-Phospho-FADD (Ser191) Polyclonal Antibody 可用于 WB,IHC。

Anti-Phospho-FADD (Ser191) Polyclonal Antibody

Anti-Phospho-FADD (Ser191) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-FADD (Ser191) Polyclonal Antibody
产品编号 TMAC-01423 别名 p-FADD (Ser191), p-FADD (S191), FADD (p-Ser191), FADD (p-S191)

Anti-Phospho-FADD (Ser191) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-FADD (Ser191)。Anti-Phospho-FADD (Ser191) Polyclonal Antibody 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,230
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in WB,IHC.
别名p-FADD (Ser191), p-FADD (S191), FADD (p-Ser191), FADD (p-S191)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using FADD (Phospho-Ser191) antibody TMAC-01423 (left) or the same antibody preincubated with blocking peptide (right).
2. Western blot analysis of extracts from Jurkat cells treated with PMA using FADD (Phospho-Ser191) Antibody TMAC-01423. The lane on the right is treated with the antigen-specific peptide.
应用
WB
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of Serine191(N-R-S(p)-G-A) derived from Mouse FADD
抗原种属
mouse
Uniprot ID
Q13158
化学信息
分子量Actual: 25 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

pFADD (Ser191)pFADD (S191)FADD (pSer191)FADD (pS191)FADD (phospho-Ser191)FADD (phospho-S191)

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