Anti-AXL Antibody (6X283)

Name: Anti-AXL Antibody (6X283)
Brand: TargetMol
SKU: TMAY-03119
Rating: 4.5 (1 reviews)

还可以

产品编号 TMAY-03119

别名 AXL receptor tyrosine kinase

Anti-AXL Antibody (6X283) 是一种 Rabbit 抗体，靶向 AXL。Anti-AXL Antibody (6X283) 可用于 ELISA(Det)。

Anti-AXL Antibody (6X283)

还可以

产品编号 TMAY-03119 别名 AXL receptor tyrosine kinase

Anti-AXL Antibody (6X283) 是一种 Rabbit 抗体，靶向 AXL。Anti-AXL Antibody (6X283) 可用于 ELISA(Det)。

规格	价格	库存	数量
20 μL	¥ 795	5日内发货
100 μL	¥ 2,284	5日内发货

大包装 & 定制

加入购物车

TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

联系我们获取更多批次信息

资源下载

产品操作手册

产品介绍

生物活性

产品描述	Anti-AXL Antibody (6X283) is a Rabbit antibody targeting AXL. Anti-AXL Antibody (6X283) can be used in ELISA(Det).
别名	AXL receptor tyrosine kinase
Ig Type	Monoclonal Rabbit IgG
克隆号	6X283
交叉反应	Mouse
应用	ELISA(Det)
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Axl Kinase (rM Axl Kinase; TMPY-01364; NP_033491.2; Met1-Pro443).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Axl receptor tyrosine kinase, together with Tyro3 and Mer, constitute the TAM family of receptor tyrosine kinases. In the nervous system, Axl and its ligand Growth-arrest-specific protein 6 (Gas6) are expressed on multiple cell types. Axl functions in dampening the immune response, regulating cytokine secretion, clearing apoptotic cells and debris, and maintaining cell survival. Axl is upregulated in various disease states, such as in the cuprizone toxicity-induced model of demyelination and in multiple sclerosis (MS) lesions, suggesting that it plays a role in disease pathogenesis. Axl expression correlates with poor prognosis in several cancers. Axl mediates multiple oncogenic phenotypes and activation of these RTKs constitutes a mechanism of chemoresistance in a variety of solid tumors. Axl contributes to cell survival, migration, invasion, metastasis and chemosensitivity justify further investigation of Axl as novel therapeutic targets in cancer. The receptor tyrosine kinase AXL is thought to play a role in metastasis. The soluble AXL receptor as a therapeutic candidate agent for treatment of metastatic ovarian cancer. GAS6/AXL targeting as an effective strategy for inhibition of metastatic tumor progression in vivo.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Mouse Axl Kinase Protein (TMPY-01364)
抗原种属	Mouse
研究领域	Receptor Tyrosine Kinases (RTKs)

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.