规格

价格

库存

数量

5 μg

¥ 428

6-8日内发货

10 μg

¥ 683

6-8日内发货

20 μg

¥ 1,130

5日内发货

50 μg

¥ 2,270

5日内发货

100 μg

¥ 4,430

5日内发货

200 μg

¥ 6,730

5日内发货

500 μg

¥ 13,800

5日内发货

1 mg

¥ 28,800

5日内发货

生物活性

产品描述	CD16/FCGR3 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is A0A140HDP8.
生物活性	Measured by its binding ability in a functional ELISA. Immobilized Rhesus FCGR3-His at 10 μg/ml (100 μl/well) can bind recombinant human IgG1 (Fc) . The EC50 of human IgG1 (Fc) is 0.35-0.81 μg/ml.
研究背景	Fc receptors bind the most common class of antibody, IgG, are called Fc gamma receptors (FcγR). FcγR is divided into three classes, Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16). CD16 protein is a multifunctional, low/intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. Mouse CD16 is encoded by a single gene, while, human CD16 is expressed as two distinct forms (CD16a/FcγRIIIa and CD16b/FcγRIIIb) encoded by two different highly homologous genes in a cell type-specific manner. CD16 is involved in phagocytosis, secretion of enzymes, inflammatory mediators, antibody-dependent cellular cytotoxicity (ADCC), and clearance of immune complexes.
种属	Rhesus
表达系统	HEK293 Cells
标签	C-His
蛋白编号	A3RFZ7
蛋白构建	A DNA sequence encoding the rhesus CD16 (NP_001258584.1) extracellular domain (Met 1-Gly 206) was fused with a polyhistidine tag at the C-terminus. Predicted N terminal: Gly 17
蛋白纯度	> 95 % as determined by SDS-PAGE
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名	Fc receptor, IgG, low affinity III
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	22.7 kDa (predicted)

储存&溶解度

运输方式

In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.

存储

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

CD16/FCGR3 Protein, Rhesus, Recombinant (His)

CD16/FCGR3 Protein, Rhesus, Recombinant (His)

产品介绍

引用文献

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