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Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cytochrome P450 1A1+1A2。Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 可用于 WB。
Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cytochrome P450 1A1+1A2。Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody is a Rabbit antibody targeting Cytochrome P450 1A1+1A2. Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rat,Dog,Cow,Rabbit,Sheep) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Endoplasmic reticulum |
| 组织特异性 | Lung, lymphocytes and placenta. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008] |
| 免疫原 | KLH conjugated synthetic peptide: human Cytochrome P450 1A1 + 1A2 |
| 抗原种属 | Human |
| 基因名称 | CYP1A1 |
| 基因ID | |
| 蛋白名称 | Cytochrome P450 1A1 |
| Uniprot ID | |
| 功能 | Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene. |
| 分子量 | Theoretical: 58 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |