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Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody

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货号 TMAB-04925

Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cytochrome P450 1A1+1A2。Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 可用于 WB。

Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody

Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04925

Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cytochrome P450 1A1+1A2。Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody is a Rabbit antibody targeting Cytochrome P450 1A1+1A2. Anti-Cytochrome P450 1A1+1A2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum
组织特异性Lung, lymphocytes and placenta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human Cytochrome P450 1A1 + 1A2
抗原种属
Human
基因名称
CYP1A1
基因ID
蛋白名称
Cytochrome P450 1A1
Uniprot ID
功能
Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies; the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.
化学信息
分子量Theoretical: 58 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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