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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-VAC14 Polyclonal Antibody

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货号 TMAB-14038

Anti-VAC14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VAC14。Anti-VAC14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-VAC14 Polyclonal Antibody

Anti-VAC14 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14038

Anti-VAC14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 VAC14。Anti-VAC14 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-VAC14 Polyclonal Antibody is a Rabbit antibody targeting VAC14. Anti-VAC14 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Zebrafish)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endosome membrane. Microsome membrane. Mainly associated with membranes of the late endocytic pathway.
组织特异性Ubiquitously expressed.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE (Sbrissa et al., 2007 [PubMed 17556371]).[supplied by OMIM, Feb 2010]
抗原信息
免疫原
KLH conjugated synthetic peptide: human VAC14
抗原种属
Human
基因名称
VAC14
基因ID
55697
蛋白名称
Protein VAC14 homolog
Uniprot ID
Q08AM6
功能
The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate (PtdIns(3)P) and phosphatidylinositol 5-phosphate (PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles (ECV) / multivesicular bodies (MVB) transport intermediates from early endosomes.
化学信息
分子量Theoretical: 88 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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