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HK3 Protein, Human, Recombinant (His & GST)

Synonyms: HXK3, HKIII, hexokinase 3 (white cell)
货号 TMPY-04462 一键复制产品信息
Rating icon 很棒
26年秋季促销
26年新产品线折扣促销活动

Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues, hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, except for hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.

HK3 Protein, Human, Recombinant (His & GST)

一键复制产品信息
Rating icon 很棒
26年秋季促销
26年新产品线折扣促销活动
货号 TMPY-04462

别名 HXK3, HKIII, hexokinase 3 (white cell)

Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues, hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, except for hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.

HK3 Protein, Human, Recombinant (His & GST)
规格价格库存数量
5 μg
¥ 476
现货
10 μg
¥ 773
现货
20 μg
¥ 1,280
现货
50 μg
¥ 2,530
现货
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实验操作小课堂
常见问题解答
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纯度: > 85 % as determined by SDS-PAGE
颜色: 无色透明
性状: Solution
资源下载: COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues, hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, except for hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.
生物活性
Kinase activity untested
研究背景
Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues, hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, except for hexokinase type IV which has only one. This organization is believed to be the result of a duplication and tandem fusion event involving the gene encoding for the ancestral hexokinase. The gene encodes hexokinase-3. Similar to hexokinases-1 and hexokinases-2, this allosteric enzyme is inhibited by its product glucose 6-phosphate.
种属
Human
表达系统
Baculovirus Insect Cells
标签
His, GST
蛋白编号P52790
蛋白构建
A DNA sequence encoding the human HK3 (P52790) (Met 1-Val 923) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. Predicted N terminal: Met
蛋白纯度
> 85 % as determined by SDS-PAGE
蛋白性状
Solution
缓冲液
Supplied as sterile 50 mM Tris, 100 mM Nacl, pH7.4, 25% glycerol, 0.5 mM PMSF, 0.1 mM EDTA, 0.5 mM GSH.
复溶方法
A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名
HXK3, HKIII, hexokinase 3 (white cell)
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量127 kDa (predicted); 115 kDa (reducing conditions)
储存&溶解度
运输方式Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.
存储

It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

white cellHXK-3HXK 3hexokinase 3
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