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顶部生物活性储存和溶解信息计算器

Anti-MRC1 Antibody (6M291)

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Anti-MRC1 Antibody (6M291)
产品编号 TMAC-02449
别名 MRC1L1, MRC1, MMR, Macrophage mannose receptor 1-like protein 1, Macrophage mannose receptor 1, Human mannose receptor (hMR), C-type lectin domain family 13 member D-like, C-type lectin domain family 13 member D, CLEC13DL, CLEC13D, CD206

Anti-MRC1 Antibody (6M291) 是一种 Rabbit 抗体，靶向 MRC1。Anti-MRC1 Antibody (6M291) 可用于 WB,ICC/IF。

Anti-MRC1 Antibody (6M291)

Anti-MRC1 Antibody (6M291)

Rating icon 还可以
Anti-MRC1 Antibody (6M291)
产品编号 TMAC-02449 别名 MRC1L1, MRC1, MMR, Macrophage mannose receptor 1-like protein 1, Macrophage mannose receptor 1, Human mannose receptor (hMR), C-type lectin domain family 13 member D-like, C-type lectin domain family 13 member D, CLEC13DL, CLEC13D, CD206

Anti-MRC1 Antibody (6M291) 是一种 Rabbit 抗体，靶向 MRC1。Anti-MRC1 Antibody (6M291) 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-MRC1 Antibody (6M291) is a Rabbit antibody targeting MRC1. Anti-MRC1 Antibody (6M291) can be used in WB,ICC/IF.
别名MRC1L1, MRC1, MMR, Macrophage mannose receptor 1-like protein 1, Macrophage mannose receptor 1, Human mannose receptor (hMR), C-type lectin domain family 13 member D-like, C-type lectin domain family 13 member D, CLEC13DL, CLEC13D, CD206
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of Mannose Receptor on different lysates using anti-Mannose Receptor antibody at 1/1,000 dilution. Positive control: Lane 1: Human lung, Lane 2: HepG2, Lane 3: 293T.
2. ICC staining Mannose Receptor in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Mannose Receptor in MCF-7 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Mannose Receptor in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
推荐剂量
WB: 1:1000-5000; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景CD206, also known as macrophage mannose receptor type C (MMR or MRC1), is a type I membrane receptor protein. It is an phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P22897
化学信息
分子量Theoretical: 166/140 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

MRC1L 1MRC 1hMRCD 206

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