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Anti-mouse CD86 Antibody (1E806)

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货号 TMAB-08955

Anti-mouse CD86 Antibody (1E806) 是一种 Rat 抗体，靶向 mouse CD86。Anti-mouse CD86 Antibody (1E806) 可用于 FCM,WB。

Anti-mouse CD86 Antibody (1E806)

Anti-mouse CD86 Antibody (1E806)

一键复制产品信息
Rating icon 还可以
货号 TMAB-08955

Anti-mouse CD86 Antibody (1E806) 是一种 Rat 抗体，靶向 mouse CD86。Anti-mouse CD86 Antibody (1E806) 可用于 FCM,WB。

规格价格库存数量
100 μg
¥ 1,865
5日内发货
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产品介绍

生物活性
产品描述
Anti-mouse CD86 Antibody (1E806) is a Rat antibody targeting mouse CD86. Anti-mouse CD86 Antibody (1E806) can be used in FCM,WB.
Ig Type
Rat IgG2a, k
克隆号
1E806
反应种属
Mouse
应用FCMWB
推荐剂量
FCM: 1μg/Test; WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rat
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Expressed by activated B-lymphocytes and monocytes.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].
抗原信息
基因名称
CD86
基因ID
56822
蛋白名称
T-lymphocyte activation antigen CD86
功能
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
化学信息
分子量Theoretical: 31 kDa. Actual: 72-74 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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