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Anti-DHRS2 Polyclonal Antibody

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货号 TMAB-05130

Anti-DHRS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DHRS2。Anti-DHRS2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-DHRS2 Polyclonal Antibody

Anti-DHRS2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05130

Anti-DHRS2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DHRS2。Anti-DHRS2 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

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产品描述
Anti-DHRS2 Polyclonal Antibody is a Rabbit antibody targeting DHRS2. Anti-DHRS2 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景DHRS2 is a 258 amino acid protein that localizes to the nucleus and belongs to the short-chain dehydrogenase/reductase (SDR) family. Functioning as an NADPH-dependent dicarbonyl reductase, DHRS2 is thought to inhibit cell replication by either converting cortisone in cortisol, or by catalyzing the oxidation of androgen and estrogen. The gene encoding DHRS2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DHRS2
抗原种属
Human
基因名称
DHRS2
基因ID
10202
蛋白名称
Dehydrogenase/reductase SDR family member 2, mitochondrial
Uniprot ID
Q13268
功能
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. May inhibit cell replication.
化学信息
分子量Theoretical: 27 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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