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AKR1C4 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P17516.

| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 683 | 6-8日内发货 | |
| 10 μg | ¥ 1,130 | 6-8日内发货 | |
| 20 μg | ¥ 1,930 | 5日内发货 | |
| 50 μg | ¥ 4,430 | 5日内发货 |
| 生物活性 | Activity has not been tested. It is theoretically active, but we cannot guarantee it. |
| 产品描述 | AKR1C4 Protein, Human, Recombinant (His) is expressed in E. coli. The accession number is P17516. |
| 种属 | Human |
| 表达系统 | E. coli |
| 标签 | N-6His |
| 蛋白编号 | P17516 |
| 别名 | HAKRA,DD-4,DD4,CHDR,CDR,C11,aldo-keto reductase family 1, member C4,AKR1C4,3-α-HSD,3-alpha-HSD |
| 蛋白构建 | Met1-Tyr323 |
| 蛋白纯度 | > 90% as determined by SDS-PAGE. |
| 分子量 | 39.3 kDa (Predicted); 35-40 kDa (Reducing conditions) |
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
| 蛋白性状 | Solution |
| 缓冲液 | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, pH 8.0. |
| 复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| 运输方式 | Solutions are shipping with dry ice. |
| 研究背景 | Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity. |