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Anti-VSIG4 Antibody (4U482) 是一种 Rabbit 抗体,靶向 VSIG4。Anti-VSIG4 Antibody (4U482) 可用于 ELISA,ELISA(Det)。
Anti-VSIG4 Antibody (4U482) 是一种 Rabbit 抗体,靶向 VSIG4。Anti-VSIG4 Antibody (4U482) 可用于 ELISA,ELISA(Det)。
产品描述 | Anti-VSIG4 Antibody (4U482) is a Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody (4U482) can be used in ELISA,ELISA(Det). |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4U482 |
交叉反应 | Human |
应用 | ELISA,ELISA(Det) |
推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human VSIG4 (rh VSIG4; TMPY-01907; Q9Y279-1; Met 1-Pro 283). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. Mouse VSIG4 is synthesized as a 28 amino acid precursor that contains a signal sequence, a V-type I g domain (aa 36-115), one potential N-linked glycosylation site, and a single transmembrane domain. The V-type I g domain of mouse VSIG4 shares 86% and 8% aa sequence identity with the V-type I g domains of rat and human VSIG4, respectively. |
偶联 | Unconjugated |
其他可选修饰符 | HRP |
可提供抗体种类 | 2 |
免疫原 | Recombinant Human VSIG4 protein (TMPY-01907) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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