购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-MTMR14 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09071

Anti-MTMR14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MTMR14。Anti-MTMR14 Polyclonal Antibody 可用于 WB。

Anti-MTMR14 Polyclonal Antibody

Anti-MTMR14 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-09071

Anti-MTMR14 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 MTMR14。Anti-MTMR14 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-MTMR14 Polyclonal Antibody is a Rabbit antibody targeting MTMR14. Anti-MTMR14 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Found in reticular structures and plasma membrane ruffles. Concentrated near the nucleus.
组织特异性Expressed in various tissues, including heart, skeletal muscle, placenta, liver, lung, kidney and pancreas.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Myotubularin-related protein 14 (MTMR14), also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1). Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1). MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2). MTMR14 has also been shown to play a role in autophagy, a process that is highly regulated by phosphatidylinositides through the type III PI3K, Vps34 (3). MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3). In these studies, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition. In zebrafish, MTMR14 knockdown was shown to increase the number of autophagosomes, suggesting that its activity is associated with an inhibition of autophagy (4).
抗原信息
免疫原
KLH conjugated synthetic peptide: human MTMR14
抗原种属
Human
基因名称
MTMR14
基因ID
64419
蛋白名称
Myotubularin-related protein 14
Uniprot ID
Q8NCE2
功能
Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3.
化学信息
分子量Theoretical: 72 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-MTMR14 Polyclonal Antibody | purchase Anti-MTMR14 Polyclonal Antibody | Anti-MTMR14 Polyclonal Antibody cost | order Anti-MTMR14 Polyclonal Antibody | Anti-MTMR14 Polyclonal Antibody molecular weight