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Anti-IKK- alpha Antibody (4P589)
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产品编号 TMAC-02125
别名 TCF16, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor, Nuclear factor NFkappaB inhibitor kinase alpha, Nuclear factor NF kappa B inhibitor kinase alpha, Nuclear Factor Kappa B Inhibitor Kinase alpha, NFKBIKA, Inhibitor Of Nuclear Factor Kappa B Kinase alpha Subunit, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells, IKKα, IKKalpha, IKKA, IKK1, IKK α, IKK alpha, IKK a kinase, IKK A, IKK 1, IKBKA, IkB kinase alpha subunit, IkappaB kinase, I Kappa B Kinase alpha, I Kappa B Kinase 1, Conserved helix loop ubiquitous kinase, Conserved Helix Loop Helix Ubiquitous Kinase, CHUK1, CHUK
Anti-IKK- alpha Antibody (4P589) 是一种 Rabbit 抗体，靶向 IKK- alpha。Anti-IKK- alpha Antibody (4P589) 可用于 WB,ICC/IF,IHC,IP,FCM。
Anti-IKK- alpha Antibody (4P589)
Anti-IKK- alpha Antibody (4P589)
还可以产品编号 TMAC-02125 别名 TCF16, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor, Nuclear factor NFkappaB inhibitor kinase alpha, Nuclear factor NF kappa B inhibitor kinase alpha, Nuclear Factor Kappa B Inhibitor Kinase alpha, NFKBIKA, Inhibitor Of Nuclear Factor Kappa B Kinase alpha Subunit, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells, IKKα, IKKalpha, IKKA, IKK1, IKK α, IKK alpha, IKK a kinase, IKK A, IKK 1, IKBKA, IkB kinase alpha subunit, IkappaB kinase, I Kappa B Kinase alpha, I Kappa B Kinase 1, Conserved helix loop ubiquitous kinase, Conserved Helix Loop Helix Ubiquitous Kinase, CHUK1, CHUK
Anti-IKK- alpha Antibody (4P589) 是一种 Rabbit 抗体，靶向 IKK- alpha。Anti-IKK- alpha Antibody (4P589) 可用于 WB,ICC/IF,IHC,IP,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-IKK- alpha Antibody (4P589) is a Rabbit antibody targeting IKK- alpha. Anti-IKK- alpha Antibody (4P589) can be used in WB,ICC/IF,IHC,IP,FCM. |
| 别名 | TCF16, Nuclear Factor Of Kappa Light Chain Gene Enhancer In B Cells Inhibitor, Nuclear factor NFkappaB inhibitor kinase alpha, Nuclear factor NF kappa B inhibitor kinase alpha, Nuclear Factor Kappa B Inhibitor Kinase alpha, NFKBIKA, Inhibitor Of Nuclear Factor Kappa B Kinase alpha Subunit, Inhibitor Of Kappa Light Polypeptide Gene Enhancer In B Cells, IKKα, IKKalpha, IKKA, IKK1, IKK α, IKK alpha, IKK a kinase, IKK A, IKK 1, IKBKA, IkB kinase alpha subunit, IkappaB kinase, I Kappa B Kinase alpha, I Kappa B Kinase 1, Conserved helix loop ubiquitous kinase, Conserved Helix Loop Helix Ubiquitous Kinase, CHUK1, CHUK |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of IKK alpha on Jurkat cells lysates using anti-IKK alpha antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-IKK alpha antibody. Counter stained with hematoxylin. 3. ICC staining IKK alpha in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Hela cells with IKK alpha antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The transcription factor NFkB is retained in the cytoplasm in an inactive form by the inhibitory protein IkB. Activation of NFkB requires that IkB be phosphorylated on specific serine residues, which results in targeted degradation of IkB. IkB kinase a (IKKa), previously designated CHUK, interacts with IkB-a and specifically phosphorylates IkB-a on Ser 32 and 36, the sites that trigger its degradation. IKKa appears to be critical for NFkB activation in response to proinflammatory cytokines. Phosphorylation of IkB by IKKa is stimulated by the NFkB inducing kinase (NIK), which itself is a central regulator for NFkB activation in response to TNF and IL-1. The functional IKK complex contains three subunits, IKKa, IKKb and IKKg (also designated NEMO), and each appear to make essential contributions to IkB phosphorylation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 85 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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