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Anti-CXCR2 Polyclonal Antibody
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产品编号 TMAB-00506
Anti-CXCR2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CXCR2。Anti-CXCR2 Polyclonal Antibody 可用于 WB。
Anti-CXCR2 Polyclonal Antibody
Anti-CXCR2 Polyclonal Antibody
还可以产品编号 TMAB-00506
Anti-CXCR2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 CXCR2。Anti-CXCR2 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
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产品介绍
生物活性
抗原信息
| 产品描述 | Anti-CXCR2 Polyclonal Antibody is a Rabbit antibody targeting CXCR2. Anti-CXCR2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Sample: Lane 1: Raw264.7 (Mouse) Cell Lysate at 30 μg Lane 2: U937 (Human) Cell Lysate at 30 μg Primary: Anti-CXCR2 (TMAB-00506) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45/55 kDa Observed band size: 59 kDa 2. Sample: Lane 1: Human THP-1 cell lysates Lane 2: Human U937 cell lysates Lane 3: Human HL60 cell lysates Lane 4: Human HepG2 cell lysates Primary: Anti-CXCR2 (TMAB-00506) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 55 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究背景 | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009]. |
| 免疫原 | KLH conjugated synthetic peptide: human CXCR2 |
| 抗原种属 | Human |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | GPCR,SARS Coronavirus,Other cell division antibodies |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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