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TGFBR1 Protein, Human, Recombinant (mFc & Avi)
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货号 TMPK-00305
别名 tβR-I, TGFβRI, TGF-β RI, TGFR-1, TGF-bRI, TGFBR1, TGFbetaRI, TGF-beta RI, TGFB1R1, tbetaR-I, SKR4, LDS2A, LDS1A, ALK-5, ACVRLK4, AAT5
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
其他形式的 “TGFBR1 Protein, Human, Recombinant (mFc & Avi)”:
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
一键复制产品信息 很棒SPR兼容缓冲液
货号 TMPK-00305 别名 tβR-I, TGFβRI, TGF-β RI, TGFR-1, TGF-bRI, TGFBR1, TGFbetaRI, TGF-beta RI, TGFB1R1, tbetaR-I, SKR4, LDS2A, LDS1A, ALK-5, ACVRLK4, AAT5
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 447 | 现货 | |
| 10 μg | ¥ 723 | 现货 | |
| 20 μg | ¥ 1,190 | 3日内发货 | |
| 50 μg | ¥ 2,360 | 现货 | |
| 100 μg | ¥ 3,980 | 现货 | |
| 200 μg | ¥ 7,820 | 5日内发货 | |
| 500 μg | ¥ 19,200 | 5日内发货 |
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产品介绍
生物活性
化学信息
储存&溶解度
| 产品描述 | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. |
| 生物活性 | Human TGFBR1, mFc Tag captured on CM5 Chip via Protein A can bind Human Mature TGF beta 1, No Tag with an affinity constant of 0.35 μM as determined in SPR assay.  |
| 研究背景 | transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-mFc-Avi |
| 蛋白编号 | P36897-1 |
| 蛋白构建 | Leu34-Glu125 |
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC   |
| 蛋白性状 | Lyophilized powder |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | tβR-I, TGFβRI, TGF-β RI, TGFR-1, TGF-bRI, TGFBR1, TGFbetaRI, TGF-beta RI, TGFB1R1, tbetaR-I, SKR4, LDS2A, LDS1A, ALK-5, ACVRLK4, AAT5 |
| 内毒素 | < 1 EU/μg by the LAL method. |
| 分子量 | 38.2 kDa (predicted). Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result. |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. |
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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