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Anti-TIE2 Antibody-PE (1E654)
还可以产品编号 TMAY-01087P
Anti-TIE2 Antibody-PE (1E654) 是一种 PE-conjugated Mouse 抗体，靶向 TIE2。Anti-TIE2 Antibody-PE (1E654) 可用于 FCM。
Anti-TIE2 Antibody-PE (1E654)
Anti-TIE2 Antibody-PE (1E654)
还可以产品编号 TMAY-01087P
Anti-TIE2 Antibody-PE (1E654) 是一种 PE-conjugated Mouse 抗体，靶向 TIE2。Anti-TIE2 Antibody-PE (1E654) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-TIE2 Antibody-PE (1E654) is a PE-conjugated Mouse antibody targeting TIE2. Anti-TIE2 Antibody-PE (1E654) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 1E654 |
| 交叉反应 | Human |
| 验证活性 | Profile of anti-Human TIE2 (CD202b) reactivity on HUVEC cells analyzed by flow cytometry. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Tie2 / CD202b / TEK (rh Tie2 / CD202b / TEK; TMPY-01064; AAA61139.1; Met1-Lys745) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | TEK, or TIE-2, is an endothelial cell-specific receptor tyrosine kinase (RTK) that is known as a functioning molecule of vascular endothelial cells. TEK comprises a subfamily of RTK with TIE, and these two receptors play critical roles in vascular maturation, maintenance of integrity and remodeling. Targeted mutagenesis of both Tek and its agonistic ligand, Angiopoietin-1, result in embryonic lethality, demonstrating that the signal transduction pathways mediated by this receptor are crucial for normal embryonic development. TEK signaling is indispensable for the development of the embryonic vasculature and suggests that TEK signaling may also be required for the development of the tumor vasculature. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human Tie2 / CD202b / TEK protein (TMPY-01064) |
| 抗原种属 | Human |
| 研究领域 | Receptor Tyrosine Kinases (RTKs), Cancer Drug Targets, Hemangioblast Markers |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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