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Anti-GPHA2 Antibody (9X922) 是一种 Rabbit 抗体,靶向 GPHA2。Anti-GPHA2 Antibody (9X922) 可用于 ELISA。
Anti-GPHA2 Antibody (9X922) 是一种 Rabbit 抗体,靶向 GPHA2。Anti-GPHA2 Antibody (9X922) 可用于 ELISA。
产品描述 | Anti-GPHA2 Antibody (9X922) is a Rabbit antibody targeting GPHA2. Anti-GPHA2 Antibody (9X922) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 9X922 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human GPHA2 / glycoprotein hormone alpha 2 (rh GPHA2 / glycoprotein hormone alpha 2; TMPY-03784; Q96T91; Met1-Tyr129). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The alpha-subunit combines with four distinct beta-subunits giving rise to four biologically active hormones in the human: FSH, LH, TSH, and CG. GPHA2 and glycoprotein hormone beta 5 (GPHB5) can form a noncovalent heterodimer. GPHA2 can be detected in a variety of tissues. Recombinant A2/B5 heterodimeric glycoproteins activate human TSH receptors, but not LH and FSH receptors, and shows high affinity to TSH receptors in a radioligand receptor assay. The heterodimer also stimulates cAMP production and thymidine incorporation by cultured thyroid cells and increases serum thyroxine levels in TSH-suppressed rats in vivo. This new heterodimeric glycoprotein hormone was named Thyrostimulin based on its thyroid-stimulating activity. The expression of Thyrostimulin in the anterior pituitary known to express TSH receptors suggested a paracrine mechanism. |
偶联 | Unconjugated |
免疫原 | Recombinant Human GPHA2 / glycoprotein hormone alpha 2 Protein (TMPY-03784) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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