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Anti-GPHA2 Antibody (9X922)

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产品编号 TMAY-02653

Anti-GPHA2 Antibody (9X922) 是一种 Rabbit 抗体,靶向 GPHA2。Anti-GPHA2 Antibody (9X922) 可用于 ELISA。

Anti-GPHA2 Antibody (9X922)

Anti-GPHA2 Antibody (9X922)

Rating icon 还可以
产品编号 TMAY-02653

Anti-GPHA2 Antibody (9X922) 是一种 Rabbit 抗体,靶向 GPHA2。Anti-GPHA2 Antibody (9X922) 可用于 ELISA。

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产品介绍

生物活性
产品描述
Anti-GPHA2 Antibody (9X922) is a Rabbit antibody targeting GPHA2. Anti-GPHA2 Antibody (9X922) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
9X922
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human GPHA2 / glycoprotein hormone alpha 2 (rh GPHA2 / glycoprotein hormone alpha 2; TMPY-03784; Q96T91; Met1-Tyr129).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景GPHA2 is a member of the glycoprotein hormones subunit alpha family. Glycoprotein hormones consist of two subunits, the common alpha- and specific beta-subunits, which associate noncovalently to form a heterodimer. The alpha-subunit combines with four distinct beta-subunits giving rise to four biologically active hormones in the human: FSH, LH, TSH, and CG. GPHA2 and glycoprotein hormone beta 5 (GPHB5) can form a noncovalent heterodimer. GPHA2 can be detected in a variety of tissues. Recombinant A2/B5 heterodimeric glycoproteins activate human TSH receptors, but not LH and FSH receptors, and shows high affinity to TSH receptors in a radioligand receptor assay. The heterodimer also stimulates cAMP production and thymidine incorporation by cultured thyroid cells and increases serum thyroxine levels in TSH-suppressed rats in vivo. This new heterodimeric glycoprotein hormone was named Thyrostimulin based on its thyroid-stimulating activity. The expression of Thyrostimulin in the anterior pituitary known to express TSH receptors suggested a paracrine mechanism.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human GPHA2 / glycoprotein hormone alpha 2 Protein (TMPY-03784)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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