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Anti-SEMA4D Antibody (5L831) 是一种 Mouse 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (5L831) 可用于 ELISA。
Anti-SEMA4D Antibody (5L831) 是一种 Mouse 抗体,靶向 SEMA4D。Anti-SEMA4D Antibody (5L831) 可用于 ELISA。
产品描述 | Anti-SEMA4D Antibody (5L831) is a Mouse antibody targeting SEMA4D. Anti-SEMA4D Antibody (5L831) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 5L831 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SEMA4D / CD100 (rh SEMA4D / CD100; TMPY-01906; AAH54500.1; Met 1-Arg 734). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous systems. VEGF and SEMA4D had a positive correlation with the malignant degree of ovarian cancer, and SEMA4D can serve as an independent prognostic factor. SEMA4D was the first semaphorin described to have immune functions and serves important roles in T cell priming, antibody production, and cell-to-cell adhesion. Proteolytic cleavage of SEMA4D from the cell surface gives rise to a soluble fragment of SEMA4D (sSEMA4D). Similar to the transmembranal form, sSEMA4D is thought to have immunoregulatory properties. |
偶联 | Unconjugated |
免疫原 | Recombinant Human SEMA4D / CD100 protein (TMPY-01906) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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