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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301)

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货号 TMAB-07758

Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) 是一种 Mouse 抗体，靶向 Interleukin-1 receptor-like 1/ST2。Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) 可用于 WB。

Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301)

Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07758

Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) 是一种 Mouse 抗体，靶向 Interleukin-1 receptor-like 1/ST2。Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) 可用于 WB。

规格价格库存数量
200 μg
¥ 5,585
5日内发货
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) is a Mouse antibody targeting Interleukin-1 receptor-like 1/ST2. Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) can be used in WB.
Ig Type
IgG
克隆号
1K301
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Isoform C: Cell membrane.Isoform B: Secreted. Cell membrane; Single-pass type I membrane protein.
组织特异性Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M PBS (pH7.4).
研究背景ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP.
抗原信息
免疫原
Recombinant Protein: human human Interleukin-1 receptor-like 1/ST2 protein
抗原种属
Human
基因名称
IL1RL1
基因ID
9173
蛋白名称
Interleukin-1 receptor-like 1
Uniprot ID
Q01638
功能
Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function.
化学信息
分子量Theoretical: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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