Anti-TLR2 Antibody (3U29)

Name: Anti-TLR2 Antibody (3U29)
Brand: TargetMol
SKU: TMAY-00203
Rating: 4.5 (1 reviews)

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产品编号 TMAY-00203

Anti-TLR2 Antibody (3U29) 是一种 Rabbit 抗体，靶向 TLR2。Anti-TLR2 Antibody (3U29) 可用于 FCM。

Anti-TLR2 Antibody (3U29)

还可以

产品编号 TMAY-00203

Anti-TLR2 Antibody (3U29) 是一种 Rabbit 抗体，靶向 TLR2。Anti-TLR2 Antibody (3U29) 可用于 FCM。

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生物活性

产品描述	Anti-TLR2 Antibody (3U29) is a Rabbit antibody targeting TLR2. Anti-TLR2 Antibody (3U29) can be used in FCM.
Ig Type	Monoclonal Rabbit IgG
克隆号	3U29
交叉反应	Human
验证活性	Flow cytometric analysis of Human TLR2(CD282) expression on human whole blood monocytes. Cells were stained with purified anti-Human TLR2(CD282), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用	FCM
推荐剂量	FCM: 1:25-1:100
抗体种类	Monoclonal
宿主来源	Rabbit
构建方式	This antibody was obtained from a rabbit immunized with purified, recombinant Human TLR2 / CD282 (rh TLR2 / CD282; NP_003255.2Met1-Arg587).
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathogen recognition and activation of innate immunity. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 contains 14 LRR (leucine-rich) repeats and 1 TIR domain. TLR2 gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. CD282 cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. It also cooperates with TLR1 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. CD282 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It may also promote apoptosis in response to lipoproteins.

偶联与修饰

偶联	Unconjugated
其他可选修饰符	APC/Biotin/FITC/PE
可提供抗体种类	5

抗原信息

免疫原	Recombinant Human TLR2 / CD282 Protein
抗原种属	Human
研究领域	Neuroinflammation

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.