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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Cytokeratin 2e Antibody (2U710)

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货号 TMAB-04951

Anti-Cytokeratin 2e Antibody (2U710) 是一种 Rabbit 抗体，靶向 Cytokeratin 2e。Anti-Cytokeratin 2e Antibody (2U710) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

Anti-Cytokeratin 2e Antibody (2U710)

Anti-Cytokeratin 2e Antibody (2U710)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04951

Anti-Cytokeratin 2e Antibody (2U710) 是一种 Rabbit 抗体，靶向 Cytokeratin 2e。Anti-Cytokeratin 2e Antibody (2U710) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

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产品描述
Anti-Cytokeratin 2e Antibody (2U710) is a Rabbit antibody targeting Cytokeratin 2e. Anti-Cytokeratin 2e Antibody (2U710) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,ELISA.
Ig Type
IgG
克隆号
2U710
反应种属
Human
应用WBIHC-PIHC-FrICC/IFIFELISA
推荐剂量
WB: 1:500-1000; IHC-P: 1:50-200; IHC-Fr: 1:50-200; ICC/IF: 1:50-200; IF: 1:50-200; ELISA: 1:5000-10000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic.
组织特异性Expressed in the upper spinous and granular suprabasal layers of normal adult epidermal tissues from most body sites including thigh, breast nipple, foot sole, penile shaft and axilla. Not present in foreskin, squamous metaplasias and carcinomas. Expression in hypertrophic and keloid scars begins in the deepest suprabasal layer. Weakly expressed in normal gingival and tongue, however expression is induced in benign keratoses of lingual mucosa and in mild-to-moderate oral dysplasia with orthokeratinization.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
Recombinant Protein: human Cytokeratin 2e protein, around 350-500aa
抗原种属
Human
基因名称
KRT2
基因ID
3849
蛋白名称
Keratin, type II cytoskeletal 2 epidermal
Uniprot ID
P35908
功能
Keratins are the major gene product of keratinocytes and form the intermediate filament cytoskeletal network in these cells. In cells of the upper spinous layer, KRT2E and KRT9 are expressed. Although the expression of KRT9 is limited to palmoplantar epidermis, KRT2E is expressed not only in this tissue but also in other regions, notably the epidermis covering the knee, thigh, and groin. It is not known whether these keratins simply replace their respective type I or type II counterpart in the preexisting KRT1/KRT10 network or dimerize with another, as yet undiscovered keratin partner.
化学信息
分子量Theoretical: 70 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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