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Anti-XRCC1 Antibody (5W492)
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产品编号 TMAC-04300
别名 XRCC1_HUMAN, XRCC 1, X ray repair, complementing defective, repair in Chinese hamster, X ray repair cross-complementing protein 1, X ray repair cross complementing protein 1, X ray repair cross complementing 1, X ray repair complementing defective repair in chinese hamster cells 1, X ray Repair Complementing Defective Repair in Chinese Hamster Cells, X ray repair complementing defective repair in chinese hamster, RCC, DNA repair protein XRCC1
Anti-XRCC1 Antibody (5W492) 是一种 Rabbit 抗体，靶向 XRCC1。Anti-XRCC1 Antibody (5W492) 可用于 WB,IHC。
Anti-XRCC1 Antibody (5W492)
Anti-XRCC1 Antibody (5W492)
还可以产品编号 TMAC-04300 别名 XRCC1_HUMAN, XRCC 1, X ray repair, complementing defective, repair in Chinese hamster, X ray repair cross-complementing protein 1, X ray repair cross complementing protein 1, X ray repair cross complementing 1, X ray repair complementing defective repair in chinese hamster cells 1, X ray Repair Complementing Defective Repair in Chinese Hamster Cells, X ray repair complementing defective repair in chinese hamster, RCC, DNA repair protein XRCC1
Anti-XRCC1 Antibody (5W492) 是一种 Rabbit 抗体，靶向 XRCC1。Anti-XRCC1 Antibody (5W492) 可用于 WB,IHC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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| 产品描述 | Anti-XRCC1 Antibody (5W492) is a Rabbit antibody targeting XRCC1. Anti-XRCC1 Antibody (5W492) can be used in WB,IHC. |
| 别名 | XRCC1_HUMAN, XRCC 1, X ray repair, complementing defective, repair in Chinese hamster, X ray repair cross-complementing protein 1, X ray repair cross complementing protein 1, X ray repair cross complementing 1, X ray repair complementing defective repair in chinese hamster cells 1, X ray Repair Complementing Defective Repair in Chinese Hamster Cells, X ray repair complementing defective repair in chinese hamster, RCC, DNA repair protein XRCC1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000; IHC: 1:50-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The x-ray repair cross-complementing (XRCC) proteins are responsible for efficiently repairing and maintaining genetic stability following DNA base damage. These genes share sequence similarity with the yeast DNA repair protein Rad5. XRCC1 is a protein that facilitates the DNA base excision repair pathway by interacting with DNA ligase III and DNA polymerase to repair DNA single-strand breaks. XRCC2 and XRCC3 are both involved in maintaining chromosome stability during cell division. XRCC2 is required for efficient repair of DNA double-strand breaks by homologous recombination between sister chromatids, and XRCC3 interacts directly with Rad51 to cooperate with Rad51 during recombinational repair. XRCC4 is an accessory factor of DNA ligase IV that preferentially binds DNA with nicks or broken ends. XRCC4 binds to DNA ligase IV and enhances its joining activity, and it is also involved in V(D)J recombination. Any defect in one of the known components of the DNA repair/V(D)J recombination machinery (Ku-70, Ku-80, DNA-PKCS, XRCC4 and DNA ligase IV) leads to abortion of the V(D)J rearrangement process and early block in both T and B cell maturation. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 100/70 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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