Afalanine

Name: Afalanine
Brand: TargetMol
SKU: T1106
Price: 123 CNY
Availability: InStock
Rating: 5 (10 reviews)

一键复制产品信息

很棒

纯度: 99.03%

货号 T1106Cas号 2901-75-9

别名 阿丙氨酸, N-Acetyl-DL-phenylalanine

Afalanine (N-Acetyl-DL-phenylalanine) 是抗抑郁药。

Afalanine

一键复制产品信息

很棒

纯度: 99.03%

货号 T1106 别名 阿丙氨酸, N-Acetyl-DL-phenylalanineCas号 2901-75-9

Afalanine (N-Acetyl-DL-phenylalanine) 是抗抑郁药。

规格	价格	库存
50 mg	¥ 123	现货
100 mg	¥ 163	现货
200 mg	¥ 226	现货
500 mg	¥ 359	现货
1 g	¥ 518	现货
5 g	¥ 1,260	现货
1 mL x 10 mM (in DMSO)	¥ 179	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

加入购物车

TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.03%

联系我们获取更多批次信息

资源下载:

COA HNMR HPLC 产品操作手册

产品介绍

Afalanine AI Summary

Afalanine exhibits a complex profile with both physicochemical properties and a variety of bioactivities. It has a bitter threshold value of Log 1/T = 1.96 and its partition coefficient (logP) shows discrepancies: one source reports LogP = 2.37, typically suggesting moderate lipophilicity, whereas another source reports LogP = -0.7, indicating higher water solubility and potential hydrophilicity, which can significantly influence its bioavailability and distribution. Bioactivity assays reveal that Afalanine acts as an inhibitor of AmpC Beta-Lactamase (1412.5 nM), HP1-beta Chromodomain Interactions with methylated histone tails (8912.5 nM), and has activity in a Schwann cell PMP22 intronic element firefly luciferase assay (405.3 nM). It also induces DNA re-replication in SW480 colon adenocarcinoma cells (3662.6 nM), and blocks entry of the Ebola Virus (AC50 values range from 2818.4 nM to 44.67 µM). Additionally, Afalanine shows high inhibition of sodium fluorescein uptake in OATP1B3-transfected CHO cells (112.49%) and OATP1B1-transfected CHO cells (114.23%) at 10 µM. Moreover, it demonstrates antiviral activity against SARS-CoV-2, requiring a concentration of greater than 19,952.62 nM to achieve 50% inhibition of virus-induced cytotoxicity in VERO-6 cells after 48 hours..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Afalanine (N-Acetyl-DL-phenylalanine) is a kind of Amino Acids and Derivatives.
别名	阿丙氨酸, N-Acetyl-DL-phenylalanine

化学信息

分子量	207.23
分子式	C₁₁H₁₃NO₃
CAS No.	2901-75-9
Smiles	CC(=O)NC(Cc1ccccc1)C(O)=O
密度	1.199 g/cm3
颜色	White
物理性状	Solid

储存&溶解度

存储

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 60 mg/mL (289.53 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8256 mL	24.1278 mL	48.2556 mL	241.2778 mL
5 mM	0.9651 mL	4.8256 mL	9.6511 mL	48.2556 mL
10 mM	0.4826 mL	2.4128 mL	4.8256 mL	24.1278 mL
20 mM	0.2413 mL	1.2064 mL	2.4128 mL	12.0639 mL
50 mM	0.0965 mL	0.4826 mL	0.9651 mL	4.8256 mL
100 mM	0.0483 mL	0.2413 mL	0.4826 mL	2.4128 mL