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HSPG2 Protein, Human, Recombinant (His & Myc)

HSPG2 Protein, Human, Recombinant (His & Myc)

产品编号 TMPH-00996

HSPG2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.

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HSPG2 Protein, Human, Recombinant (His & Myc)
规格 价格/CNY 货期 数量
20 μg ¥ 3,910 20日内发货
100 μg ¥ 10,900 20日内发货
1 mg ¥ 46,000 20日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: HSPG2 Protein, Human, Recombinant (His & Myc) (TMPH-00996)
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生物活性
技术参数
产品性质
产品描述 HSPG2 Protein, Human, Recombinant (His & Myc) is expressed in HEK293.
种属 Human
表达系统 HEK293 Cells
标签 N-10xHis, C-Myc
蛋白编号 P98160
氨基酸序列 DAPGQYGAYFHDDGFLAFPGHVFSRSLPEVPETIELEVRTSTASGLLLWQGVEVGEAGQGKDFISLGLQDGHLVFRYQLGSGEARLVSEDPINDGEWHRVTALREGRRGSIQVDGEELVSGRSPGPNVAVNAKGSVYIGGAPDVATLTGGRFSSGITGCVKNLVLHSARPGAPPPQPLDLQHRAQAGANTRPCPS
蛋白构建 4197-4391 aa
蛋白纯度 > 85% as determined by SDS-PAGE.
分子量 25.6 kDa (predicted)
缓冲液 Tris-based buffer, 50% glycerol
复溶方法 A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development.; Endorepellin in an anti-angiogenic and anti-tumor peptide that inhibits endothelial cell migration, collagen-induced endothelial tube morphogenesis and blood vessel growth in the chorioallantoic membrane. Blocks endothelial cell adhesion to fibronectin and type I collagen. Anti-tumor agent in neovascularization. Interaction with its ligand, integrin alpha2/beta1, is required for the anti-angiogenic properties. Evokes a reduction in phosphorylation of receptor tyrosine kinases via alpha2/beta1 integrin-mediated activation of the tyrosine phosphatase, PTPN6.; The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity.

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Keywords

recombinant recombinant-proteins proteins protein

 

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