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Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog

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货号 TMPH-01195

别名 Viral interleukin-10 homolog, vIL-10, UL111A, cmvIL-10

Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is F5HC71.

Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog
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Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog

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货号 TMPH-01195 别名 Viral interleukin-10 homolog, vIL-10, UL111A, cmvIL-10

Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is F5HC71.

规格价格库存数量
5 μg
¥ 998
20日内发货
10 μg
¥ 1,660
20日内发货
20 μg
¥ 2,790
20日内发货
50 μg
¥ 3,790
20日内发货
100 μg
¥ 4,830
20日内发货
200 μg
¥ 6,880
20日内发货
500 μg
¥ 11,500
20日内发货
1 mg
¥ 16,800
20日内发货
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产品介绍

生物活性
产品描述
Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells. Human cytomegalovirus (HCMV) (strain Merlin) Viral interleukin-10 homolog is expressed in E. coli expression system. The predicted molecular weight is 17.5 kDa and the accession number is F5HC71.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Functional viral IL-10 homolog. Can bind to the human IL-10 receptor and compete with human IL-10 for binding sites. Requires both subunits of the human IL-10 receptor complex to induce signal transduction events and biological activities. IL-10 signaling pathway has several immunosuppressive activities that are exploited by the virus. Inhibits TLR-induced type I interferon production in host plasmacytoid dendritic cells.
种属
HCMV
表达系统
E. coli
标签Tag Free
蛋白编号F5HC71
氨基酸序列ATTTTIKNTKPQCRPEDYATRLQDLRVTFHRVKPTLQREDDYSVWLDGTVVKGCWGCSVMDWLLRRYLEIVFPAGDHVYPGLKTELHSMRSTLESIYKDMRQCPLLGCGDKSVISRLSQEAERKSDNGTRKGLSELDTLFSRLEEYLHSRK
蛋白构建26-176 aa
蛋白纯度
> 90% as determined by SDS-PAGE.
缓冲液Tris-based buffer, 50% glycerol
复溶方法A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
别名Viral interleukin-10 homolog, vIL-10, UL111A, cmvIL-10
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量17.5 kDa (predicted)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.

关键词

vIL10cmvIL10
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