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Anti-CDH12 Antibody (3X709)
还可以产品编号 TMAY-00601
Anti-CDH12 Antibody (3X709) 是一种 Mouse 抗体，靶向 CDH12。Anti-CDH12 Antibody (3X709) 可用于 ELISA。
Anti-CDH12 Antibody (3X709)
Anti-CDH12 Antibody (3X709)
还可以产品编号 TMAY-00601
Anti-CDH12 Antibody (3X709) 是一种 Mouse 抗体，靶向 CDH12。Anti-CDH12 Antibody (3X709) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CDH12 Antibody (3X709) is a Mouse antibody targeting CDH12. Anti-CDH12 Antibody (3X709) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 3X709 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Cadherin-12 / CDH12 (rh Cadherin-12 / CDH12; Catalog #10317-H08H; NP_001783.2; Met 1-Ala 605). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Classic Cadherins represent a family of calcium-dependent homophilic cell-cell adhesion molecules. They confer strong adhesiveness to animal cells when they are anchored to the actin cytoskeleton via their cytoplasmic binding partners, catenins. The cadherin/catenin adhesion system plays key roles in the morphogenesis and function of the vertebrate and invertebrate nervous systems. Furthermore, this system is involved in synaptic plasticity. Recent studies on the role of individual cadherin subtypes at synapses indicate that individual cadherin subtypes play their own unique role to regulate synaptic activities. Type II (atypical) cadherins are defined based on their lack of an HAV cell adhesion recognition sequence specific to type I cadherins. It has been observed that cells containing a specific cadherin subtype tend to cluster together to the exclusion of other types, both in cell culture and during development. Cadherin-12 also known as CDH12, is a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin-12 appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human Cadherin-12 / CDH12 Protein (TMPY-01172) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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