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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KLHDC2 Polyclonal Antibody

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货号 TMAB-08099

Anti-KLHDC2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KLHDC2。Anti-KLHDC2 Polyclonal Antibody 可用于 WB。

Anti-KLHDC2 Polyclonal Antibody

Anti-KLHDC2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08099

Anti-KLHDC2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KLHDC2。Anti-KLHDC2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-KLHDC2 Polyclonal Antibody is a Rabbit antibody targeting KLHDC2. Anti-KLHDC2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Cow,Horse,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Widely expressed, with high levels in skeletal muscle, heart, pancreas and liver. Undetectable in peripheral blood leukocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景KLHDC2 is a 406 amino acid protein that contains six kelch repeats. Localizing to the nucleus, KLHDC2 is widely expressed, with high levels found in muscle, heart, pancreas and liver. KLHDC2 interacts directly with CREB3, repressing CREB3-mediated transcription. Existing as two alternatively spliced isoforms, the gene encoding KLHDC2 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KLHDC2
抗原种属
Human
基因名称
KLHDC2
基因ID
23588
蛋白名称
Kelch domain-containing protein 2
Uniprot ID
Q9Y2U9
功能
Represses CREB3-mediated transcription by interfering with CREB3-DNA binding.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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