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Anti-Phospho-STAT4 (Tyr693) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-STAT4 (Tyr693)。Anti-Phospho-STAT4 (Tyr693) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Phospho-STAT4 (Tyr693) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-STAT4 (Tyr693)。Anti-Phospho-STAT4 (Tyr693) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-Phospho-STAT4 (Tyr693) Polyclonal Antibody is a Rabbit antibody targeting Phospho-STAT4 (Tyr693). Anti-Phospho-STAT4 (Tyr693) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
疾病造模方案 | |
别名 | STAT4 (p-Y693), STAT4 (p-Tyr693), SLEB11, signal transducer and activator of transcription 4, p-STAT4 (Y693), p-STAT4 (Tyr693) |
Ig Type | IgG |
交叉反应 | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
验证活性 | Paraformaldehyde-fixed, paraffin embedded (mouse intestine tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Phospho-Stat4 (Tyr693)) Polyclonal Antibody, Unconjugated (TMAB-01511) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining. |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation. |
构建方式 | Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
浓度 | 1 mg/mL |
研究背景 | The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]. |
免疫原 | KLH conjugated Synthesised phosphopeptide: human Stat4 around the phosphorylation site of Tyr693 |
抗原种属 | Human |
基因名称 | STAT4 |
基因ID | |
蛋白名称 | Signal transducer and activator of transcription 4 |
Uniprot ID | |
研究领域 | STAT family,STATs,Other factors,Phosphoprotein ICE kits,STATs |
功能 | Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling. |
分子量 | Theoretical: 82 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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