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Anti-Ribonuclease 3/ECP Polyclonal Antibody

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货号 TMAB-12250

Anti-Ribonuclease 3/ECP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ribonuclease 3/ECP。Anti-Ribonuclease 3/ECP Polyclonal Antibody 可用于 WB,ICC/IF。

Anti-Ribonuclease 3/ECP Polyclonal Antibody

Anti-Ribonuclease 3/ECP Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-12250

Anti-Ribonuclease 3/ECP Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Ribonuclease 3/ECP。Anti-Ribonuclease 3/ECP Polyclonal Antibody 可用于 WB,ICC/IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Ribonuclease 3/ECP Polyclonal Antibody is a Rabbit antibody targeting Ribonuclease 3/ECP. Anti-Ribonuclease 3/ECP Polyclonal Antibody can be used in WB,ICC/IF.
Ig Type
IgG
反应种属
Human
验证活性
1. Confocal immunofluorescent analysis of RNASE3 Antibody (C-term) (Cat#TMAB-12250) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
2. RNASE3 Antibody (C-term) (Cat. #TMAB-12250) western blot analysis in NCI-H460 cell line lysates (35 μg/lane). This demonstrates the RNASE3 antibody detected the RNASE3 protein (arrow).
3. Western blot analysis of lysate from human spleen tissue lysate, using RNASE3 Antibody (C-term) (Cat. #TMAB-12250). AP13557b was diluted at 1:1000. A goat anti-rabbit IgG H&l (HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 35 ug.
应用WBICC/IF
推荐剂量
WB: 1:500-2000; ICC/IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasmic granule. Matrix of eosinophil's large specific granule.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景ECP is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis, and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases
抗原信息
免疫原
KLH conjugated synthetic peptide: human Ribonuclease 3
抗原种属
Human
基因名称
RNASE3
基因ID
6037
蛋白名称
Eosinophil cationic protein
Uniprot ID
P12724
功能
Cytotoxin and helminthotoxin with low-efficiency ribonuclease activity. Possesses a wide variety of biological activities. Exhibits antibacterial activity.
化学信息
分子量Theoretical: 16 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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