购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空

Anti-BCL2 Antibody (3D343)

Rating icon 还可以
产品编号 TMAH-00109
别名 PPP1R50, Bcl-2, B-cell CLL/lymphoma 2

Anti-BCL2 Antibody (3D343) 是一种抗体,靶向 BCL2。Anti-BCL2 Antibody (3D343) 可用于 ELISA, WB, IHC。

Anti-BCL2 Antibody (3D343)

Anti-BCL2 Antibody (3D343)

Rating icon 还可以
产品编号 TMAH-00109 别名 PPP1R50, Bcl-2, B-cell CLL/lymphoma 2

Anti-BCL2 Antibody (3D343) 是一种抗体,靶向 BCL2。Anti-BCL2 Antibody (3D343) 可用于 ELISA, WB, IHC。

规格价格库存数量
50 μL
¥ 1,305
5日内发货
100 μL
¥ 2,190
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报,不能被用于人体,我们不向个人提供产品和服务。请您遵守承诺用途,不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载

产品介绍

生物活性
产品描述
Anti-BCL2 Antibody (3D343) is an antibody targeting BCL2. Anti-BCL2 Antibody (3D343) can be used in ELISA, WB, IHC.
别名PPP1R50, Bcl-2, B-cell CLL/lymphoma 2
Ig Type
Rabbit IgG
克隆号
3D343
交叉反应
Human, Mouse
验证活性
1. Western Blot
-Positive WB detected in: 293 whole cell lysate, HepG2 whole cell lysate, Jurkat whole cell lysate, U-937 whole cell lysate, THP-1 whole cell lysate, Raji whole cell lysate, Mouse Spleen whole cell lysate
-All lanes: Bcl-2 antibody at 1:1000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 27, 23 kDa
-Observed band size: 27 kDa
2. IHC image of TMAH-00109 diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
应用
ELISA, WB, IHC
推荐剂量
WB:1:500-1:5000; IHC:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Mitochondrion outer membrane; Single-pass membrane protein. Nucleus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). Also acts as an inhibitor of autophagy: interacts with BECN1 and AMBRA1 during non-starvation conditions and inhibits their autophagy function. May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human Bcl-2
抗原种属
Human
基因ID
596
Uniprot ID
研究领域
Cancer, Cell biology, Metabolism, Signal transduction
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

SCI 文献

计算器

  • 稀释 计算器

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

Related Tags: buy Anti-BCL2 Antibody (3D343) | purchase Anti-BCL2 Antibody (3D343) | Anti-BCL2 Antibody (3D343) cost | order Anti-BCL2 Antibody (3D343)