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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-KIR2DL4 Polyclonal Antibody

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货号 TMAB-08074

Anti-KIR2DL4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KIR2DL4。Anti-KIR2DL4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-KIR2DL4 Polyclonal Antibody

Anti-KIR2DL4 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08074

Anti-KIR2DL4 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 KIR2DL4。Anti-KIR2DL4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-KIR2DL4 Polyclonal Antibody is a Rabbit antibody targeting KIR2DL4. Anti-KIR2DL4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the "framework" loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CD158
抗原种属
Human
基因名称
KIR2DL4
基因ID
3805
蛋白名称
Killer cell immunoglobulin-like receptor 2DL4
Uniprot ID
Q99706
功能
Receptor on natural killer (NK) cells for HLA-C alleles. Inhibits the activity of NK cells thus preventing cell lysis.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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