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Anti-ATM Monoclonal Antibody (7T10) 是一种 Mouse 抗体,靶向 ATM。Anti-ATM Monoclonal Antibody (7T10) 可用于 IHC,IF,FCM。
别名 TELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1
Anti-ATM Monoclonal Antibody (7T10) 是一种 Mouse 抗体,靶向 ATM。Anti-ATM Monoclonal Antibody (7T10) 可用于 IHC,IF,FCM。

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| 产品描述 | Anti-ATM Monoclonal Antibody (7T10) is a Mouse antibody targeting ATM. Anti-ATM Monoclonal Antibody (7T10) can be used in IHC,IF,FCM. |
| 别名 | TELO1, TEL1, ATE, ATDC, ATD, ATC, ATA, AT1 |
| Ig Type | IgG2b |
| 克隆号 | 7T10 |
| 反应种属 | Human, Mouse, Monkey, Rat |
| 应用 | IHCIFFCM |
| 推荐剂量 | IHC: 1/200-1/1000; IF: 1/200-1/1000; FCM: 1/200-1/400 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | PBS with 0.05% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of human ATM (AA: 2577-3056) expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | ATM |
| 基因ID | |
| 蛋白名称 | Serine-protein kinase ATM |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |