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Nectin-2 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00293

别名 PVRR2, PVRL2, PRR2, Nectin2, MPH, HVEB, CD112

Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.

Nectin-2 Protein, Human, Recombinant (His & Avi)

Nectin-2 Protein, Human, Recombinant (His & Avi)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPK-00293 别名 PVRR2, PVRL2, PRR2, Nectin2, MPH, HVEB, CD112

Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.

规格价格库存数量
5 μg
¥ 283
3日内发货
10 μg
¥ 446
3日内发货
20 μg
¥ 723
3日内发货
50 μg
¥ 1,380
3日内发货
100 μg
¥ 2,360
现货
200 μg
¥ 4,280
5日内发货
500 μg
¥ 9,490
5日内发货
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选择批次:
纯度: > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC
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产品介绍


生物活性
产品描述
Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.
生物活性
1. Immobilized Human Nectin-2, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Human PVRIG, mFc Tag with the EC50 of 0.15μg/ml determined by ELISA (QC Test). 2. Human PVRIG, mFc Tag captured on CM5 Chip via anti-mouse antibody can bind Human Nectin-2, His Tag with an affinity constant of 0.349 μM as determined in SPR assay.
研究背景
Nectin-2 is an adhesion molecule that has been reported to play a role in tumor growth, metastasis and tumor angiogenesis. Nectin-2 expression in ovarian cancer may support tumor cell adhesion, leading to growth and lymph node metastasis. Effect of VEGF on Nectin-2 expression as well as permeability was investigated in HUVEC.
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号Q92692-2
蛋白构建Gln32-Leu360
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名PVRR2, PVRL2, PRR2, Nectin2, MPH, HVEB, CD112
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量38.4 kDa (predicted). Due to glycosylation, the protein migrates to 45-52 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
  • 比活力 计算器

剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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