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Anti-PDXK Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PDXK。Anti-PDXK Polyclonal Antibody 可用于 FCM。
Anti-PDXK Polyclonal Antibody 是一种 Rabbit 抗体,靶向 PDXK。Anti-PDXK Polyclonal Antibody 可用于 FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-PDXK Polyclonal Antibody is a Rabbit antibody targeting PDXK. Anti-PDXK Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Dog,Horse) |
| 应用 | FCM |
| 推荐剂量 | FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Ubiquitous. Isoform 3 is detected in adult testis and spermatozoa. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Pyridoxal kinase belongs to the pyridoxine kinase family and phosphorylates vitamin B6, a step necessary for the conversion of vitamin B6 to pyridoxal 5’ phosphate (PLP), the active form of vitamin B6. PLP acts as a coenzyme and functions to maintain homeostasis. Pyridoxal kinase is a 312-amino acid cytoplasmic protein that may act as a homodimer and is expressed ubiquitously. There are three known isoforms of pyridoxal kinase, and isoform 3 expression is observed in adult testis and spermatozoa. The optimum pH for pyridoxal kinase is between 5.5 and 6.0. PDXK, the gene that encodes the pyridoxal kinase protein, maps to chromosome 21q22.3 and may be a candidate gene for autoimmune polyglandular disease type 1, a genetic disorder that has been mapped to the same region on chromosome 21. |
| 免疫原 | KLH conjugated synthetic peptide: human PDXK |
| 抗原种属 | Human |
| 基因名称 | PDXK |
| 基因ID | |
| 蛋白名称 | Pyridoxal kinase |
| Uniprot ID | |
| 功能 | Required for synthesis of pyridoxal-5-phosphate from vitamin B6. |
| 分子量 | Theoretical: 35 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |