Myristoyl coenzyme A lithium is a myristoylated form of coenzyme A (CoA). Myristoylation, an essential process in viruses, is typically regulated by N-myristoyltransferase (NMT), which is more active in colon epithelial tumors than in normal cells. The reduced form of coenzyme A (CoA) is a key regulator of NMT activity, whereas the oxidized form does not permit NMT to promote myristoylation. Myristoyl coenzyme A potentially inhibits demyristoylation, suggesting anticancer and antiviral mechanisms.