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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-mGluR5 Polyclonal Antibody 2

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货号 TMAB-08794

Anti-mGluR5 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 mGluR5。Anti-mGluR5 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-mGluR5 Polyclonal Antibody 2

Anti-mGluR5 Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-08794

Anti-mGluR5 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 mGluR5。Anti-mGluR5 Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-mGluR5 Polyclonal Antibody 2 is a Rabbit antibody targeting mGluR5. Anti-mGluR5 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GRM5
抗原种属
Human
基因名称
GRM5
基因ID
2915
蛋白名称
Metabotropic glutamate receptor 5
Uniprot ID
P41594
功能
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteKns) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
化学信息
分子量Theoretical: 132 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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