UBE2H Protein, Human, Recombinant (GST)

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

规格	价格/CNY		数量
10 μg	￥ 220	5日内发货
50 μg	￥ 580	5日内发货
500 μg	￥ 4,970	5日内发货
1 mg	￥ 7,110	5日内发货

规格

价格/CNY

货期

数量

10 μg

￥ 220

5日内发货

50 μg

￥ 580

5日内发货

500 μg

￥ 4,970

5日内发货

1 mg

￥ 7,110

5日内发货

产品描述

种属	Human
表达系统	E. coli
标签	N-GST
蛋白编号	P62256
别名	UBE2H, UbcH2, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin-Protein Ligase H, Ubiquitin Carrier Protein H, Ubiquitin-Conjugating Enzyme E2-20K
氨基酸序列	Met1-Leu183
蛋白构建	Met1-Leu183
蛋白纯度	Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
分子量	50 KDa (reducing condition)

内毒素	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液	Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

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UBE2H Protein, Human, Recombinant (GST)

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