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UBE2H Protein, Human, Recombinant (GST)

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货号 TMPJ-01047

别名 Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

UBE2H Protein, Human, Recombinant (GST)
其他形式的 “UBE2H Protein, Human, Recombinant (GST)”:
Ube2H Protein, Human, RecombinantTMPY-02607
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UBE2H Protein, Human, Recombinant (GST)

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货号 TMPJ-01047 别名 Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2

Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

规格价格库存数量
5 μg
¥ 148
6-8日内发货
10 μg
¥ 220
6-8日内发货
20 μg
¥ 327
5日内发货
50 μg
¥ 580
5日内发货
100 μg
¥ 1,080
5日内发货
200 μg
¥ 1,980
5日内发货
1 mg
¥ 7,110
5日内发货
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选择批次:
纯度: Greater than 90% as determined by reducing SDS-PAGE.
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.
种属
Human
表达系统
E. coli
标签N-GST
蛋白编号P62256
氨基酸序列Met1-Leu183
蛋白构建Met1-Leu183
蛋白纯度
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
缓冲液Supplied as a 0.2 μm filtered solution of 50 mM HEPES, 150 mM NaCl, 2 mM DTT, 10% Glycerol, pH 7.5.
别名Ubiquitin-Protein Ligase H, Ubiquitin-Conjugating Enzyme E2-20K, Ubiquitin-Conjugating Enzyme E2 H, Ubiquitin Carrier Protein H, UBE2H, UbcH2
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量50 KDa (reducing condition)
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

计算器

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剂量转换

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技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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