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别名 Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle
Anti-Alpha actinin Antibody (8E638) 是一种 Mouse 抗体,靶向 Alpha actinin。Anti-Alpha actinin Antibody (8E638) 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。
Anti-Alpha actinin Antibody (8E638) 是一种 Mouse 抗体,靶向 Alpha actinin。Anti-Alpha actinin Antibody (8E638) 可用于 ELISA,ICC/IF,IF,IHC-Fr,IHC-P。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,790 | 5日内发货 |
| 产品描述 | Anti-Alpha actinin Antibody (8E638) is a Mouse antibody targeting Alpha actinin. Anti-Alpha actinin Antibody (8E638) can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P. |
| 别名 | Non-Muscle alpha-Actinin-1, FLJ54432, FLJ40884, F-Actin Cross-Linking Protein, BDPLT15, alpha-actinin-1, alpha-actinin cytoskeletal isoform, alpha Actinin 1, ACTN1, ACTN 1, Actinin, alpha 1, Actinin alpha 1, Actinin 1 Smooth Muscle |
| Ig Type | IgG |
| 克隆号 | 8E638 |
| 交叉反应 | (predicted:Human,Mouse,Rat) |
| 应用 | ELISAICC/IFIFIHC-FrIHC-P |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:500-1000; ICC/IF: 1:100-500; IF: 1:500-1000; ELISA: 1:5000-10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| 免疫原 | Recombinant Protein: human Alpha-actinin-1 protein 1-205/894 (C-6x His-Tag) |
| 抗原种属 | Human |
| 基因名称 | ACTN1 |
| 基因ID | |
| 蛋白名称 | alpha-actinin-1 |
| Uniprot ID | |
| 研究领域 | Mesoderm,Actin Binding Proteins,Actin Crosslinking,Mesoderm |
| 功能 | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| 分子量 | Theoretical: 103 kDa. |
| 颜色 | Transparent |
| 物理性状 | Liquid |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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