购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空
顶部生物活性储存和溶解信息计算器

Anti-EpCAM/TROP1 Antibody (7L889)

Rating icon 还可以
Anti-EpCAM/TROP1 Antibody (7L889)
产品编号 TMAY-01073
别名 TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5

Anti-EpCAM/TROP1 Antibody (7L889) 是一种 Mouse 抗体，靶向 EpCAM/TROP1。Anti-EpCAM/TROP1 Antibody (7L889) 可用于 WB。

Anti-EpCAM/TROP1 Antibody (7L889)
331

Anti-EpCAM/TROP1 Antibody (7L889)

Rating icon 还可以
Anti-EpCAM/TROP1 Antibody (7L889)
产品编号 TMAY-01073 别名 TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5

Anti-EpCAM/TROP1 Antibody (7L889) 是一种 Mouse 抗体，靶向 EpCAM/TROP1。Anti-EpCAM/TROP1 Antibody (7L889) 可用于 WB。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-EpCAM/TROP1 Antibody (7L889) is a Mouse antibody targeting EpCAM/TROP1. Anti-EpCAM/TROP1 Antibody (7L889) can be used in WB.
别名TROP-1, TROP1, TACSTD1, MK-1, MIC18, M4S1, KSA, KS1/4, HNPCC8, ESA, epithelial cell adhesion molecule, EGP40, EGP314, EGP-2, DIAR5
Ig Type
Mouse IgG1
克隆号
7L889
交叉反应
Human
验证活性
1. Anti-EPCAM mouse monoclonal antibody at 1:500 dilution.
-Lane A: A431 Whole Cell Lysate.
-Lane B: MCF7 Whole Cell Lysate.
-Lane C: HCT116 Whole Cell Lysate.
-Lane D: COLO205 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:35 kDa.
-Observed band size:40 kDa.
2. EPCAM was immunoprecipitated using:
-Lane A:0.5 mg MCF-7 Whole Cell Lysate
-0.5 µL anti-EPCAM mouse monoclonal antibody and 15 μl of 50 % Protein G agarose.
-Primary antibody:
-Anti-EPCAM mouse monoclonal antibody, at 1:500 dilution.
-Secondary antibody:
-Dylight 800-labeled antibody to Mouse IgG (H+L), at 1:7500 dilution.
-Developed using the odyssey technique.
-Performed under reducing conditions.
-Predicted band size: 40 kDa.
-Observed band size: 40 kDa
应用
WB
推荐剂量
WB: 1:500-1:1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human EpCAM / TROP1 (rh EpCAM; TMPY-01300; NP_002345.1; Met 1-Lys 265). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF-Like repeats and a cystenin-rich region, a transmembrane domain and a cytoplasmic domain. It modulates cell adhesion and proliferation. Its overexpression has been detected in many epithelial tumours and has been associated with high stage, high grade and a worse survival in some tumour types. EpCAM has been shown to function as a calcium-independent homophilic cell adhesion molecule that does not exhibit any obvious relationship to the four known cell adhesion molecule superfamilies. However, recent insights have revealed that EpCAM participates in not only cell adhesion, but also in proliferation, migration and differentiation of cells. In addition, recent study revealed that EpCAM is the Wnt-beta-catenin signaling target gene and may be used to facilitate prognosis. It has oncogenic potential and is activated by release of its intracellular domain, which can signal into the cell nucleus by engagement of elements of the wnt pathway.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human EpCAM protein (TMPY-01300)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

TROP 1TACSTD-1TACSTD 1MK1MK 1MIC-18MIC 18HNPCC-8HNPCC 8EGP-40EGP-314EGP2EGP 40EGP 314EGP 2DIAR-5DIAR 5

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-EpCAM/TROP1 Antibody (7L889) | purchase Anti-EpCAM/TROP1 Antibody (7L889) | Anti-EpCAM/TROP1 Antibody (7L889) cost | order Anti-EpCAM/TROP1 Antibody (7L889)