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Anti-Gamma Tubulin Antibody (6F275) 是一种 Mouse 抗体,靶向 Gamma Tubulin。Anti-Gamma Tubulin Antibody (6F275) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
Anti-Gamma Tubulin Antibody (6F275) 是一种 Mouse 抗体,靶向 Gamma Tubulin。Anti-Gamma Tubulin Antibody (6F275) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 200 μg | ¥ 5,585 | 5日内发货 | |
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-Gamma Tubulin Antibody (6F275) is a Mouse antibody targeting Gamma Tubulin. Anti-Gamma Tubulin Antibody (6F275) can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 6F275 |
| 反应种属 | Human,Mouse,Rat |
| 应用 | WBIHC-PIHC-FrIFFCM |
| 推荐剂量 | WB: 1:500-5000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 亚细胞定位 | Cytoplasm, cytoskeleton, centrosome. |
| 组织特异性 | Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome. |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Protein G purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Gamma tubulin, a member of the tubulin superfamily, is a ubiquitous and highly conserved protein within the microtubule organizing centre (MTOC). Gamma tubulin is not a component of microtubules, rather it functions as the microtubule nucleator at the MOTC, is responsible for binding microtubule minus ends and mediating the link between microtubles and the centrosome. By binding to the beta tubulin subunit of the tubulin molecule, it establishes the polarity of a microtubule leaving the alpha tubulin subunit exposed at the positive end. The abundance of Gamma tubulin is less than 1% of the level of either alpha or beta tubulin. It shares approximately 28-32% identity with alpha tubulin from various organisms and 32-36% identity with beta tubulins. The detection, localization and characterization of proteins involved in microtubule function is fundamental to the understanding of mitosis, meiosis and the microtubule cytoskeleton. |
| 免疫原 | KLH conjugated synthetic peptide: human Gamma Tubulin |
| 抗原种属 | Human |
| 基因名称 | TUBG1 |
| 基因ID | |
| 蛋白名称 | Tubulin gamma-1 chain |
| Uniprot ID | |
| 功能 | Tubulin is the major constituent of microtubules. Gamma tubulin is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta tubulin minus-end nucleation, centrosome duplication and spindle formation. |
| 分子量 | Theoretical: 50 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |