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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CD39L4 Antibody (2I566)

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货号 TMAB-03972

Anti-CD39L4 Antibody (2I566) 是一种 Rabbit 抗体，靶向 CD39L4。Anti-CD39L4 Antibody (2I566) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

Anti-CD39L4 Antibody (2I566)

Anti-CD39L4 Antibody (2I566)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03972

Anti-CD39L4 Antibody (2I566) 是一种 Rabbit 抗体，靶向 CD39L4。Anti-CD39L4 Antibody (2I566) 可用于 WB,IHC-P,IHC-Fr,IP,IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍

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产品描述
Anti-CD39L4 Antibody (2I566) is a Rabbit antibody targeting CD39L4. Anti-CD39L4 Antibody (2I566) can be used in WB,IHC-P,IHC-Fr,IP,IF.
Ig Type
IgG
克隆号
2I566
反应种属
Mouse,Rat (predicted:Human)
应用WBIHC-PIHC-FrIPIF
推荐剂量
WB: 1:1000-2000; IHC-P: 1:100-200; IHC-Fr: 1:100-200; IP: 1:20-50; IF: 1:100-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane, Single-pass type II membrane protein
组织特异性Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP-glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER.
抗原信息
免疫原
A synthesized peptide: human ENTPD5
抗原种属
Human
基因名称
ENTPD5
基因ID
957
蛋白名称
Ectonucleoside triphosphate diphosphohydrolase 5
Uniprot ID
O75356
功能
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling
化学信息
分子量Theoretical: 48 kDa. Actual: 47 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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