Name: Feniralstat
Brand: TargetMol
SKU: T63507
Price: 1980 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 1,980

In stock

5 mg

¥ 4,920

In stock

10 mg

¥ 6,950

In stock

25 mg

¥ 10,600

In stock

50 mg

¥ 13,800

In stock

1 mL x 10 mM (in DMSO)

¥ 5,720

In stock

产品介绍

生物活性

产品描述	Feniralstat (KVD-824) is a selective and highly efficient kallikrein inhibitor. It can be used for researching immune system diseases and cardiovascular diseases.
靶点活性	plasma kallikrein (pKal) (human):6.7 nM
体外活性	Feniralstat （化合物 30）是一种吡唑衍生物，能够有效抑制激肽释放酶 (kallikrein)，对人血浆激肽释放酶 (pKal) 的 IC50 为 6.7 nM。Feniralstat 对人 KLK1、人 FXIa 和人因子 XIIa 的抑制作用较弱（IC50 均超过 40 μM）。[1]
别名	菲尼阿司他, KVD-824, KVD824

化学信息

分子量	509.51
分子式	C₂₆H₂₅F₂N₅O₄
CAS No.	2166320-76-7
Smiles	O=C1C=CC(F)=CN1CC2=CC=C(C=C2)CN3N=C(C(=C3)C(=O)NCC4=NC=CC(OC)=C4F)COC

储存&溶解度

存储

keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 80.00 mg/mL (157.01 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9627 mL	9.8134 mL	19.6267 mL	98.1335 mL
5 mM	0.3925 mL	1.9627 mL	3.9253 mL	19.6267 mL
10 mM	0.1963 mL	0.9813 mL	1.9627 mL	9.8134 mL
20 mM	0.0981 mL	0.4907 mL	0.9813 mL	4.9067 mL
50 mM	0.0393 mL	0.1963 mL	0.3925 mL	1.9627 mL
100 mM	0.0196 mL	0.0981 mL	0.1963 mL	0.9813 mL

体内实验配液计算器