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Anti-IL-22 Antibody (2I729)
还可以产品编号 TMAY-02449
Anti-IL-22 Antibody (2I729) 是一种 Rabbit 抗体，靶向 IL-22。Anti-IL-22 Antibody (2I729) 可用于 ELISA,ELISA(Det)。
Anti-IL-22 Antibody (2I729)
Anti-IL-22 Antibody (2I729)
还可以产品编号 TMAY-02449
Anti-IL-22 Antibody (2I729) 是一种 Rabbit 抗体，靶向 IL-22。Anti-IL-22 Antibody (2I729) 可用于 ELISA,ELISA(Det)。
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抗原信息
| 产品描述 | Anti-IL-22 Antibody (2I729) is a Rabbit antibody targeting IL-22. Anti-IL-22 Antibody (2I729) can be used in ELISA,ELISA(Det). |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 2I729 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Det) |
| 推荐剂量 | ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IL22 / Interleukin 22 (rh IL22 / Interleukin 22; TMPY-03490; NP_065386.1; Ala34-Ile179). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | IL22 is a member of a group of cytokines called the IL-1 family of IL-1 superfamily (including IL-19, IL-2, IL-24, and IL-26), a class of potent mediators of cellular inflammatory responses. It shares the use of IL-1R2 in cell signaling with other members of this family, IL-1, IL-26, IL-28A/B, and IL-29. IL22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens especially in epithelial cells such as respiratory and gut epithelial cells. IL22 along with IL-17 is rapidly produced by splenic LTi-like cells and can be also produced by Th17 cells and likely plays a role in the coordinated response of both adaptive and innate immune systems. IL22 biological activity is initiated by binding to a cell-surface complex composed of IL-22R1 and IL-1R2 receptor chains and further regulated by interactions with a soluble binding protein, IL-22BP, which shares sequence similarity with an extracellular region of IL-22R1 (SIL-22R1). IL22 and IL-1 receptor chains play a role in cellular targeting and signal transduction to selectively initiate and regulate immune responses. IL22 can contribute to immune disease through the stimulation of inflammatory responses, S1s, and defensins. IL22 also promotes hepatocyte survival in the liver and epithelial cells in the lung and gut similar to IL-1. In some contexts, the pro-inflammatory versus tissue-protective functions of IL22 are regulated by the often co-expressed cytokine IL-17A. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | HRP |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human IL22 / Interleukin 22 Protein (TMPY-03490) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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