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Anti-Cytochrome b245 Light Chain Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cytochrome b245 Light Chain。Anti-Cytochrome b245 Light Chain Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-Cytochrome b245 Light Chain Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Cytochrome b245 Light Chain。Anti-Cytochrome b245 Light Chain Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
Anti-Cytochrome b245 Light Chain Polyclonal Antibody 相关产品
产品描述 | Anti-Cytochrome b245 Light Chain Polyclonal Antibody is a Rabbit antibody targeting Cytochrome b245 Light Chain. Anti-Cytochrome b245 Light Chain Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
别名 | Superoxide-generating NADPH oxidase light chain subunit, p22-phox, p22phox, p22 phagocyte B-cytochrome, Neutrophil cytochrome b 22 kDa polypeptide, Flavocytochrome b 558 alpha polypeptide, Cytochrome b558 subunit alpha, Cytochrome b(558) alpha subunit, Cytochrome b(558) alpha chain, Cytochrome b alpha polypeptide, Cytochrome b 245 light chain, Cytochrome b 245 alpha polypeptide, CYBA, CY24A |
Ig Type | IgG |
交叉反应 | Human,Mouse (predicted:Rat) |
验证活性 | Tissue/cell: human liver carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-CYBA Polyclonal Antibody, Unconjugated (TMAB-00530) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
应用 | |
推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell Membrane |
构建方式 | Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase is present in phagocytes, neuroepithelial bodies, vascular smooth muscle cells and endothelial cells. It includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane, where they associate with the flavocytochrome cytochrome b558 to form the active enzyme complex. The p22- and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. |
免疫原 | KLH conjugated synthetic peptide: human CK18 Cytochrome b245 Light Chain/p22phox |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Cellular metabolic process,Oxidative Stress,Cytotoxic Cells,Cytochromes,Oxidative stress |
分子量 | Theoretical: 21 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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