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Anti-Adiponectin Antibody (5C908)

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产品编号 TMAY-01147

Anti-Adiponectin Antibody (5C908) 是一种 Mouse 抗体,靶向 Adiponectin。Anti-Adiponectin Antibody (5C908) 可用于 ELISA,ELISA(Det)。

Anti-Adiponectin Antibody (5C908)

Anti-Adiponectin Antibody (5C908)

Rating icon 还可以
产品编号 TMAY-01147

Anti-Adiponectin Antibody (5C908) 是一种 Mouse 抗体,靶向 Adiponectin。Anti-Adiponectin Antibody (5C908) 可用于 ELISA,ELISA(Det)。

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产品介绍

生物活性
产品描述
Anti-Adiponectin Antibody (5C908) is a Mouse antibody targeting Adiponectin. Anti-Adiponectin Antibody (5C908) can be used in ELISA,ELISA(Det).
Ig Type
Monoclonal mouse IgG1
克隆号
5C908
交叉反应
Human
应用
ELISA,ELISA(Det)
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Adiponectin (rh Adiponectin; TMPY-05556; NP_001171271.1; Met1-Asn244). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
研究背景Adiponectin (ADIPOQ), or 30 kDa adipocyte complement-related protein (Acrp30) is a protein secreted by adipose tissue, which acts to reduce insulin resistance and atherogenic damage, but it also exerts actions in other tissues. Adiponectin mediates its actions in the periphery mainly via two receptors, AdipoR1 and AdipoR2. Adiponectin influences gonadotropin release, normal pregnancy, and assisted reproduction outcomes. Adiponectin, a beneficial adipokine, represents a major link between obesity and reproduction. Higher levels of adiponectin are associated with improved menstrual function and better outcomes in assisted reproductive cycles. Unlike other adipocytokines produced by adipose tissue, adiponectin appears to have anti-inflammatory, anti-diabetic, and anti-atherogenic properties. Several clinical studies demonstrate the inverse relationship between plasma adiponectin levels and several inflammatory markers including C-reactive protein. Adiponectin attenuates inflammatory responses to multiple stimuli by modulating signaling pathways in a variety of cell types. The anti-inflammatory properties of adiponectin may be a major component of its beneficial effects on cardiovascular and metabolic disorders including atherosclerosis and insulin resistance. Additionally, it is important factor in chronic liver diseases and chronic kidney diseases. Some cancer cell types express adiponectin receptors. Thus Adiponectin may act on tumour cells directly by binding and activating adiponectin receptors and downstream signalling pathways.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Adiponectin Protein (TMPY-05556)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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