4-Amino-TEMPO is employed as a spin label to detect free radicals and the damage they cause. It mimics the activity of superoxide dismutase and can easily penetrate cells, thus safeguarding them against oxidative damage induced by H2O2. Moreover, 4-Amino-TEMPO demonstrates significant radioprotective properties, effectively shielding DNA from oxidative stress damage caused by UV irradiation by maintaining a positive charge. Additionally, 4-Amino-TEMPO serves as a highly selective oxidation catalyst and is extensively used in the development of various specialty chemicals, including fragrances and pesticides.