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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Urokinase Polyclonal Antibody

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货号 TMAB-14004

Anti-Urokinase Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Urokinase。Anti-Urokinase Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Urokinase Polyclonal Antibody

Anti-Urokinase Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-14004

Anti-Urokinase Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Urokinase。Anti-Urokinase Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-Urokinase Polyclonal Antibody is a Rabbit antibody targeting Urokinase. Anti-Urokinase Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Expressed in the prostate gland and prostate cancers.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Urokinase is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in the Urokinase gene may be associated with late onset Alzheimer disease and also with decreased affinity for fibrin binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg Val bond in plasminogen. The proprotein is cleaved at a Lys Ile bond by plasmin to form a two chain derivative in which a single disulfide bond connects the amino terminal A chain to the catalytically active, carboxy terminal B chain. This two chain derivative is also called HMW uPA (high molecular weight uPA). HMW uPA can be further processed into LMW uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino terminal fragment. LMW uPA is proteolytically active but does not bind to the uPA receptor.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PLAU
抗原种属
Human
基因名称
PLAU
基因ID
5328
蛋白名称
Urokinase-type plasminogen activator
Uniprot ID
P00749
功能
Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.
化学信息
分子量Theoretical: 49 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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